THE COMPANY

Claricell® is a registered trademark of PharmacoNutrition GmbH, Switzerland.
PharmacoNutrition is a privately held company dedicated to develop evidence based, natural nutritional programs, designed to resolve the major health problems of our time.

PharmacoNutrition has applied a rigorous pharmaceutical approach when developing and marketing our products.
This means that educating and seeking the support amongst both consumers and healthcare professionals is an important element in the company’s strategy.

All products under the PharmacoNutrition umbrella are manufactured according to GMP (Good Manufacturing Practice), and contain only well-documented and bioactive ingredients in the formulations.

PHILOSOPHY & VISION

Combining Nature & Science, we develop innovative solutions to correct and alleviate the fundamental causes of degenerative diseases.

By this, we hope to improve people’s quality of life and longevity.

Products

The Claricell® Healthy Ageing Program is designed to provide optimum immune support at all stages of life!
The platform technology in all products under the Claricell® umbrella is Wellmune®.

Wellmune®

Wellmune® is a unique and proprietary strain of beta1,3/1,6 glucan (saccharomyces cerevisiae) from Baker’s yeast, supported by more than USD 350 million in research & development.

Wellmune® is 100 % natural, gluten-free, safe for everyday consumption and clinically proven to help strengthen our immune system.

Unmatched clinical results support the effectiveness of this ingredient:

• Improves overall physical health
• Reduces upper respiratory tract infection symptoms
• Reduces harmful effects of stress
• Helps maintain healthy vigour & mental clarity
• Reduces fatigue
• Reduces the symptoms of allergies

Vitamin D3

Vitamin D is really a hormone rather than a vitamin, and is vital for the normal functioning of every system in the body, including the immune system.

Vitamin D deficiency triggers inflammation; conversely, people with adequate levels of Vitamin D in their bodies have a lower risk of cancer, arthritis, heart disease, dementia, autoimmune disease, depression and osteoporosis. There is even some evidence suggesting that a healthy Vitamin D status may help maintain a healthy weight.

Wellmune® is protected by more than 40 patents and supported by more than 13 human clinical studies.

Nutritional information per soft drop:

• 349 mg Omega-3 (261 mg Docosahexaenoic acid & 55 mg Eicosapentaenoic acid)
• 50 mg Wellmune® beta 1,3/1,6 glucans (naturally derived from Saccharomyces cerevisiae)
• 5 µg Vitamin D3 (100 % NRV*)

Directions: Children 3- 8 years old – take 1 drop daily. Children over 8 years – take 1 -2 soft drops daily.

Omega-3

Consuming enough EPA and DHA omega-3’s is important for general health. For example, sufficient intake supports the health of our hearts, brains, eyes, joints, blood vessels and more. They support healthy mood and help us live longer. Omega-3’s are critical to normal development during pregnancy, childhood, and adolescence.

The high content of DHA in Claricell Junior has great benefits for children of all ages.

Vitamin D3

Vitamin D is really a hormone rather than a vitamin, and is vital for the normal functioning of every system in the body, including the immune system.

Vitamin D deficiency triggers inflammation; conversely, people with adequate levels of Vitamin D in their bodies have a lower risk of cancer, arthritis, heart disease, dementia, autoimmune disease, depression and osteoporosis. There is even some evidence suggesting that a healthy Vitamin D status may help maintain a healthy weight.

Wellmune®

Wellmune® is a unique and proprietary strain of beta1,3/1,6 glucan (saccharomyces cerevisiae) from Baker’s yeast supported by more than USD 350 million in research & development.

Wellmune® is 100 % natural, gluten-free, safe for everyday consumption and clinically proven to help strengthen our immune system.

Unmatched clinical results support the effectiveness of the ingredient:

• Improves overall physical health
• Reduces upper respiratory tract infection symptoms
• Reduces harmful effects of stress
• Helps maintain healthy vigour & mental clarity
• Reduces fatigue
• Reduces the symptoms of allergies

Nutritional information per effervescent tablet:

• Vitamin C 1,000 mg
• Wellmune® 250 mg
• Zinc 10 mg
• Selenium 100 µg
• Vitamin D3 25 µg  

Directions: Adults & children over 12 – take 1 effervescent tablet daily with water. Do not exceed the recommended intake.

Vitamin C

Vitamin C, also known as ascorbic acid, is a water-soluble nutrient found in some foods. In the body, it acts as an antioxidant, helping to protect cells from the damage caused by free radicals. Free radicals are compounds formed when our bodies convert the food we eat into energy. People are also exposed to free radicals in the environment from cigarette smoke, air pollution, and ultraviolet light from the sun.

The body also needs Vitamin C to make collagen, a protein required to help wounds heal. In addition, vitamin C improves the absorption of iron from plant-based foods and helps the immune system work properly to protect the body from disease.

Nutritional information per VegiCap:

• Wellmune® 250 mg
• Curcumin 50 mg 
• Vitamin C 40 mg
• Vitamin E 12 mg
• Hydroxytyrosol 10 mg (as Hytolive®)
• Zinc 10 mg
• Beta-carotene 10 mg (natural)
• Vitamin B6 4.2 mg
• Copper 1 mg
• Vitamin A 800 µg
• Folate 200 µg (as Quatrefolic®)
• Vitamin K2 75 µg (as VitaMK7®)
• Selenium 55 µg
• Vitamin D3 20 µg  
• Vitamin B12 7.5 µg

Directions: Adults & children over 12 – take 1 capsule daily with water. Do not exceed the recommended intake.

Wellmune®

Wellmune® is a unique and proprietary strain of beta1,3/1,6 glucan (saccharomyces cerevisiae) from Baker’s yeast supported by more than USD 350 million in research & development.

Wellmune® is 100 % natural, gluten-free, safe for everyday consumption and clinically proven to help strengthen our immune system.

Unmatched clinical results support the effectiveness of the ingredient:

• Improves overall physical health
• Reduces upper respiratory tract infection symptoms
• Reduces harmful effects of stress
• Helps maintain healthy vigour & mental clarity
• Reduces fatigue
• Reduces the symptoms of allergies

For more information: www.wellmune.com

Curcumin 

Curcumin is the principal component of the Indian spice, turmeric (Curcuma longa), member of the ginger family (Zingiberaceae). At first, people used Curcumin as a food and later discovered its impressive medicinal qualities.

Extensive research has demonstrated that Curcumin is a powerful immune & anti-inflammatory enhancer and an anti-ageing & anti-depressant agent. It is furthermore a potential novel drug for near future to control various diseases including cancer, Alzheimer’s disease and oxidative stress-induced pathogenesis.

For more information: www.aureabiolabs.com

Vitamin C

Vitamin C, also known as ascorbic acid, is a water-soluble nutrient found in some foods. In the body, it acts as an antioxidant, helping to protect cells from the damage caused by free radicals. Free radicals are compounds formed when our bodies convert the food we eat into energy. People are also exposed to free radicals in the environment from myriad sources, amongst them: cigarette smoke, air pollution, and ultraviolet light.

The body also needs vitamin C to make collagen, a protein required to help wounds heal. In addition, vitamin C improves the absorption of iron from plant-based foods and helps the immune system work properly to protect the body from disease.

Vitamin E

Vitamin E is a fat-soluble nutrient found in many foods. In the body, it acts as an antioxidant, helping to protect cells from the damage caused by free radicals. Free radicals are compounds formed when our bodies convert the food we eat into energy. People are also exposed to free radicals in the environment from cigarette smoke, air pollution and ultraviolet light, and numerous other sources.

The body also needs vitamin E to boost its immune system so that it can fight off invading bacteria and viruses. It helps to widen blood vessels and keep blood from clotting within them. In addition, cells use vitamin E to interact with each other and to carry out many important functions.

Hydroxytyrosol (Hytolive®)

Hytolive® is an extract derived from the olive fruit water phase, containing a purity of more than 25 % of natural Hydroxytyrosol.

Hydroxytyrosol is nature’s most powerful polyphenol (natural antioxidant) and is responsible for a significant portion of the health benefits of both olives and olive oil.

The European Foods Safety Authority (EFSA) has issued a scientific opinion on health claims in relation to dietary consumption of Hydroxytyrosol and related polyphenol compounds from olive fruit and oil, and protection of blood lipids from oxidative damage which is known to adversely affect cardiovascular health

For more information: www.hytolive.com

Zinc

Zinc is an essential mineral that is involved in numerous aspects of cellular metabolism. It is required for the catalytic activity of approximately 100 enzymes and it plays a role in immune function, protein synthesis, wound healing, DNA synthesis, and cell division.

Zinc also supports normal growth and development during pregnancy, childhood and adolescence, and is required for proper sense of taste and smell. A daily intake of zinc is required to maintain a steady state because the body has no specialized zinc storage system.

Beta-carotene (natural)

Beta-carotene is a powerful antioxidant that helps protect the body against the damaging effects of free radicals, which can potentially increase the risk of developing certain diseases, including cardiovascular disease and cancer.

Beta-carotene is a safe source of Vitamin A, helping the body to reach the Vitamin A levels essential for normal growth and development, good vision and eye health, a strong immune system, and healthy skin.

Vitamin B6

Vitamin B6 is a vitamin that is naturally present in many foods. The body needs vitamin B6 for more than 100 enzyme reactions involved in metabolism. Vitamin B6 is also involved in brain development during pregnancy and infancy, as well as immune function.

Copper

Copper is one of a relatively small group of metallic elements which are essential to human health. These elements, along with amino acids, fatty acids and vitamins, are required for normal metabolic processes. However, as the body cannot synthesize copper, the human diet must supply regular amounts for absorption.

Vitamin A

Vitamin A is a fat-soluble vitamin that is naturally present in many foods. Vitamin A is important for normal vision, the immune system, and reproduction. Vitamin A also helps the heart, lungs, kidneys, and other organs work properly.

Folate (Quatrefolic®)

Quatrefolic^® represents an innovative dietary ingredient designed to act as a nutrient in all areas where folic acid and folate supplementation has been recommended and allowed.

Increasing evidence of the advantages of reduced folate vs. folic acid have been found. The rational use of reduced folate (particularly reduced and methylated, such as Quatrefolic^®), is derived from the inability of a part of the world’s population to assimilate and metabolise folic acid from food or supplements (the majority of folate consumption comes from man-made folic acid found in supplements and that added to foods).

Folic acid and food folate are not biologically active and need to be converted to the metabolically active 5-methyltetrahydrofolate (5-MTHF) through a multi-step process where the enzyme methylenetetrahydrofolate reductase (MTHFR), plays a key role. Some individuals, due to their unique genetic make-up and expression, have polymorphic forms of this enzyme and do not produce adequate or effective MTHFR.

For more information: www.quatrefolic.com

Vitamin K2 (VitaMK7®)

Vitamin K2 is a nutrient that the body needs to stay healthy. It is important for blood clotting and healthy bones, as well as other functions in the body. If you are taking a blood thinner such as warfarin (Coumadin®), it is very important to get about the same amount of vitamin K each day.

VitaMK7^® is the most advanced Vitamin K2 Menaquinone-7 product in the market

VitaMK7^® derives NATURALLY from patented bio fermentation process of Bacillus subtilis ssp natto cultures. This Bacillus is considered as the sole bacterium needed to produce good natto rich Natural Vitamin K2

VitaMK7^® is totally NATURAL and its production process DOES NOT USE ANY CHEMICALS OR SOLVENTS. This unique production process is patented is Europe, USA and Japan and guarantees: NO chemicals, NO solvents, NO additives, NO preservatives and NO synthetic processes.

For more information: www.vitamk7.com

Selenium

Selenium is a nutrient that the body needs to stay healthy. Selenium is important for thyroid gland function, DNA production, and protecting the body from damage caused by free radicals and from infection.

Vitamin D3

Vitamin D is really a hormone rather than a vitamin, and is vital for the normal functioning of every system in the body, including the immune system.

Vitamin D deficiency triggers inflammation; conversely, people with adequate levels of D in their bodies have a lower risk of cancer, arthritis, heart disease, dementia, autoimmune disease, depression and osteoporosis. There is even some evidence suggesting that a healthy D status may help maintain a healthy weight.

Vitamin B12

Vitamin B12 is a nutrient that helps keep the body’s nerve and blood cells healthy and helps make DNA, the genetic material in all cells. Vitamin B12 also helps prevent a type of anaemia called megaloblastic anaemia that makes people tired and weak.

WELLMUNE®

Wellmune® is a proprietary strain of beta1, 3/1,6 glucan (saccharomyces cerevisiae) derived from the cell wall of Baker’s yeast.

Wellmune® is 100 % natural, gluten-free, safe for everyday consumption and clinically proven to help strengthen the immune system.

The ingredient is supported by more than USD 350 million in research and development.

Claricell® with Wellmune® will keep the innate immune system active and primed, helping to kill pathogens that attack our body.

The Wellmune® mechanism of action is very well known and described in several published clinical studies.

OUR IMMUNE SYSTEM

Unmatched clinical results support the effectiveness of the ingredient:

• Improves overall physical health
• Reduces upper respiratory tract infection symptoms
• Reduces harmful effects of stress
• Helps maintain healthy vigour & mental clarity
• Reduces fatigue
• Reduces the symptoms of allergies

Our immune system is the body’s natural defence system, patrolling and protecting our body 24 hours a day, every day of our life. It protects against invasion by bacteria, viruses, parasites and fungi, and on the relatively few occasions that these gain entry to the body, it fights the resulting infection. It is also one of the body’s defences against cancer.

A weakened immune system, therefore, leaves your body vulnerable to disease. Many things can weaken the immune system such as chronic stress, a poor diet, lack of sleep, long-haul flights, heavy exercise, certain medications such as the steroids, and viruses.

The immune system is degraded in the winter months by falling levels of vitamin D, very inconveniently just when adverse weather conditions keep many at home, and in closer contact with others.

We have two distinct immune systems; the innate immune system and the adaptive, or acquired immune system.
Claricell® (Wellmune®) works foremost on the innate immune system by activating key immune cells – primarily neutrophils – which when primed, easily kill pathogens that attack our body.

The adaptive immune system is that part of the immune system with ‘memory’. It is involved (positively) in immunisation, and (negatively) in allergies and auto-immunity. Once the adaptive immune system has learned to recognise an enemy, after an initial infection or after a vaccination, it remembers the enemy’s characteristics. On second exposure to the threat, the memory cells recognise it and generate an immune response involving highly specific and effective weapons such as antibodies. That is why it is highly unusual to catch measles or the same cold twice. The adaptive immune system is powerful, sophisticated and highly specific, but it is initially slow to respond and often insufficient to protect the host against the first onslaught of a virulent bacterium or virus.

It is only able to respond rapidly and at peak effectiveness if you have already encountered the threat previously.

Even small mutations in a virus—and some viruses, like the flu virus, mutate very rapidly—may be enough to fool the adaptive immune system. Fortunately, it is only our second line of defence.

Our first line of defence is the innate immune system. In evolutionary terms, it is much older than the more sophisticated and more recently developed adaptive immune system. It is less specific; it can only recognize a limited number of compounds—around a dozen or so—that commonly occur on the surface of bacteria and yeasts. Its key cellular components are macrophages, neutrophils and Natural Killer (NK) cells.

Broadly, these ‘front line defensive troops’ constantly patrol the body and look out for anything that doesn’t belong there. If macrophages and neutrophils spot a bacterium, they swallow it and try to digest it. If NK cells recognize a virally infected cell they will kill it to prevent further viral replication, and if they encounter a cancer cell (and recognize it as cancerous) they will kill it to prevent tumor growth and spread.

All this makes the innate immune system very important indeed. Insects and other invertebrates—a group that constitutes the majority of animal species—rely solely on an innate immune system. They have no acquired immune system, and manage very well without one.
Another sign of the importance of the innate immune system is that while people born with severe lesions in the acquired immune system may live into their 30’s with adequate medical support, similar damage to the innate immune system is invariably fatal before birth. As the numbers of antibiotic resistant bacteria in our environment continue to increase, and as flu pandemics wax and wane, it makes good sense to ensure that your innate immune system is working as effectively as it should be.

PARTNERS

Wellmune® is a part of the Functional Ingredients and Actives group at Kerry, the global taste and nutrition company.

Kerry has a staff of 23,000 embedded in six continents – all with the same goal: to delight and nourish consumers across the globe with products people enjoy and feel better about.

For more information about Kerry: www.kerry.com

To assure top athletes around the world that the Claricell® products are safe to use, PharmacoNutrition has enrolled several of the company’s key products in the Informed-Sport Program. This is a quality assurance program for sports nutrition products, suppliers to the sports nutrition industry, and supplement manufacturing facilities. The program certifies that all nutritional supplements and/or ingredients that bear the Informed-Sport logo have been tested for banned substances by the world-class sports anti-doping laboratory, LGC. Athletes choosing to use accredited supplements can use the online search function to find products that have been through this rigorous certification process.